Optimizing Biomedical Stents with DEP MeshWorks: A Multi-Objective Approach
12th European LS-DYNA Conference 2019, Koblenz, Germany - Perumal Balu, Amarnath Venkata Golosu (Detroit Engineered Products), Matthieu Seulin (Dynas+ Engineering Products)
Abstract
Stent deployment for cardiovascular disease treatments demands precision and multi-objective optimization. This study presents a cutting-edge approach using DEP MeshWorks, LS-DYNA, and LS-OPT to design high-performing biomedical stents.
By leveraging advanced parametric modeling and optimization techniques, the study achieved stent designs that meet stringent criteria for final dilation diameters, minimal plastic strain, flexibility, and foreshortening constraints. The results highlight the efficiency and robustness of DEP MeshWorks for stent design optimization, offering transformative insights for the medical device industry.
Key Insights from the Study
- Objective: Design stents that balance precise dilation diameters, reduced plastic strain, and improved flexibility.
- Challenges Addressed:
- Springback and recoiling effects during crimping and dilation.
- Foreshortening and bending flexibility constraints.
- Technological Advantages:
- DEP MeshWorks enabled efficient parameterization and morphing.
- LS-OPT provided robust optimization with a DOE approach.
- LS-DYNA’s explicit solver ensured accurate simulation of deployment and mechanical behavior.
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Advanced Methodology for Stent Optimization
- Stent Modeling:
- DEP MeshWorks' stent rolling tool converted 2D geometries into 3D hex element models with high precision (Figure 2).
- Elastic-plastic material models were applied to capture deformation behaviors during deployment.
- Simulation Workflow:
- LS-DYNA used for crimping, dilation, and flexibility analysis simulations.
- Critical parameters such as von Mises stress, effective plastic strain, and bending stiffness were analyzed.
- Optimization Loop:
- LS-OPT employed Latin Hypercube Sampling for DOE, optimizing parameters like stent thickness, width, and slot length.
Transforming Stent Design with DEP MeshWorks
- The optimized stent achieved:
- Reduced plastic strain (from 0.53 to 0.47).
- Lower foreshortening (from 7% to 3%).
- Improved flexibility and reduced recoiling.
- Validation of optimized designs ensured compliance with manufacturing constraints.
This study demonstrates the transformative potential of DEP MeshWorks, coupled with LS-DYNA and LS-OPT, for multi-objective optimization in biomedical stent design. By addressing challenges like plastic strain, foreshortening, and flexibility, the study provides a robust framework for advancing stent design methodologies.
DEP MeshWorks' parametric tools and LS-DYNA's explicit solver ensure that stent designs not only meet stringent performance criteria but also streamline the development process, making it a game-changer for the medical device industry.
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